13 de agosto de 2025

Objective

This cross-sectional, observational study, conducted in nine Latin American countries, aimed to examine the association between hot flashes and insomnia, and whether the severity of vasomotor symptoms (VMS) correlates with sleep disturbances.
Method

The study collected sociodemographic and clinical data, and evaluated the presence of sleep disorders using Jenkin’s Sleep Scale (JSS-4) and menopausal symptoms using the Menopause Rating Scale (MRS) questionnaire.
Results

The study included 1185 postmenopausal women with average age 56.9 ± 5.7 years, body mass index (BMI) of 26.5 ± 5.2 kg/m² and 8.6 ± 6.4 years since menopause. Overall, 20.6% reported sleep disturbances. Compared to those without sleep problems, affected women had longer postmenopausal duration (12 ± 9.0 vs. 10.8 ± 7.8, p < 0.03), had higher BMI (27.9 ± 5.6 vs. 26.1 ± 5.0, p < 0.001), were more often smokers and homemakers, and had more comorbidities. They were also less likely to have a partner or have used menopausal hormone therapy. Sleep disturbances increased proportionally with VMS severity (p < 0.01). In multivariate analysis, sleep disorders were associated with VMS (odds ratio [OR] 4.47), psychotropic use (OR 1.84), obesity (OR 1.45) and comorbidities (OR 1.45).
Conclusion

Women with VMS were more likely to experience sleep disorders and this effect was proportional to the magnitude of the hot flashes. The study also presents several factors associated with sleep disorders in postmenopausal women that should be considered to help prevent these disturbances.
PLAIN LANGUAGE SUMMARY

This study examined the impact of hot flushes on sleep disorders in 1185 postmenopausal women, averaging 56.9 ± 5.7 years of age.

Of the total, 244 had sleep disturbances and had significantly more postmenopausal years, higher body mass index, were more frequently housewives, smoked more, used more psychotropic drugs and had more comorbidities. Conversely, they were less likely to have a partner, had fewer partners, used less MHT, and had lower sexual activity and physical activity. There were no differences in age, age at menopause, years of education, parity, sexual activity and physical activity.

A significant \association was found between the severity of hot flashes and the extent of sleep disruptions.Objective

This cross-sectional, observational study, conducted in nine Latin American countries, aimed to examine the association between hot flashes and insomnia, and whether the severity of vasomotor symptoms (VMS) correlates with sleep disturbances.
Method

The study collected sociodemographic and clinical data, and evaluated the presence of sleep disorders using Jenkin’s Sleep Scale (JSS-4) and menopausal symptoms using the Menopause Rating Scale (MRS) questionnaire.
Results

The study included 1185 postmenopausal women with average age 56.9 ± 5.7 years, body mass index (BMI) of 26.5 ± 5.2 kg/m² and 8.6 ± 6.4 years since menopause. Overall, 20.6% reported sleep disturbances. Compared to those without sleep problems, affected women had longer postmenopausal duration (12 ± 9.0 vs. 10.8 ± 7.8, p < 0.03), had higher BMI (27.9 ± 5.6 vs. 26.1 ± 5.0, p < 0.001), were more often smokers and homemakers, and had more comorbidities. They were also less likely to have a partner or have used menopausal hormone therapy. Sleep disturbances increased proportionally with VMS severity (p < 0.01). In multivariate analysis, sleep disorders were associated with VMS (odds ratio [OR] 4.47), psychotropic use (OR 1.84), obesity (OR 1.45) and comorbidities (OR 1.45).
Conclusion

Women with VMS were more likely to experience sleep disorders and this effect was proportional to the magnitude of the hot flashes. The study also presents several factors associated with sleep disorders in postmenopausal women that should be considered to help prevent these disturbances.
PLAIN LANGUAGE SUMMARY

This study examined the impact of hot flushes on sleep disorders in 1185 postmenopausal women, averaging 56.9 ± 5.7 years of age.

Of the total, 244 had sleep disturbances and had significantly more postmenopausal years, higher body mass index, were more frequently housewives, smoked more, used more psychotropic drugs and had more comorbidities. Conversely, they were less likely to have a partner, had fewer partners, used less MHT, and had lower sexual activity and physical activity. There were no differences in age, age at menopause, years of education, parity, sexual activity and physical activity.

A significant \association was found between the severity of hot flashes and the extent of sleep disruptions.

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